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Maddie Wu
Sofiia Shapovalova
Ian Mellis
Chien-Yu (Chihiro) Huang
Hsiang Hong
Yogesh Goyal
Kristin Daniel
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Sofiia Shapovalova
Kristin Daniel
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Yogesh Goyal
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Maddie Wu
Chien-Yu (Chihiro) Huang
Hsiang Hong
Principal Investigator
Ian Mellis
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papers
VYD2311 is a promising candidate for passive immunization against COVID-19 in immunocompromised individuals
LP. 8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting
Variant-specific antibody correlates of protection against SARS-CoV-2 Omicron symptomatic and overall infections
Antibody evasion and receptor binding of SARS-CoV-2 LP.8.1.1, NB.1.8.1, XFG, and related subvariants
Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2
Do Existing COVID-19 Vaccines Need to Be Updated in 2025?
Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
KP.2-based monovalent mRNA vaccines robustly boost antibody responses to SARS-CoV-2
Robust SARS-CoV-2-neutralizing antibodies sustained through 6 months post XBB.1.5 mRNA vaccine booster
Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineages
Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells
SARS-CoV-2 Omicron BA.2.87.1 Exhibits Higher Susceptibility to Serum Neutralization Than EG.5.1 and JN.1
XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against XBB subvariants and JN.1
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells
Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells
SARS-CoV-2 Neutralizing Antibodies After Bivalent vs. Monovalent Booster
Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells
Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity
in vitro
Association of Neighborhood-Level Factors and COVID-19 Infection Patterns in Philadelphia Using Spatial Regression
Genetic screening for single-cell variability modulators driving therapy resistance
Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility
Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting
ClampFISH detects individual nucleic acid molecules using click chemistry–based amplification
Visualizing adenosine to inosine RNA editing in single mammalian cells
An Alzheimer’s disease-derived biomarker signature identifies Parkinson’s disease patients with dementia
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another?
Conditionals by inversion provide a universal method for the generation of conditional alleles
paper
VYD2311 is a promising candidate for passive immunization against COVID-19 in immunocompromised individuals
LP. 8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting
Variant-specific antibody correlates of protection against SARS-CoV-2 Omicron symptomatic and overall infections
Antibody evasion and receptor binding of SARS-CoV-2 LP.8.1.1, NB.1.8.1, XFG, and related subvariants
Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2
Do Existing COVID-19 Vaccines Need to Be Updated in 2025?
Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
KP.2-based monovalent mRNA vaccines robustly boost antibody responses to SARS-CoV-2
Robust SARS-CoV-2-neutralizing antibodies sustained through 6 months post XBB.1.5 mRNA vaccine booster
Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN.1 sublineages
Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells
SARS-CoV-2 Omicron BA.2.87.1 Exhibits Higher Susceptibility to Serum Neutralization Than EG.5.1 and JN.1
XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against XBB subvariants and JN.1
Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells
Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells
SARS-CoV-2 Neutralizing Antibodies After Bivalent vs. Monovalent Booster
Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells
Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity
in vitro
Association of Neighborhood-Level Factors and COVID-19 Infection Patterns in Philadelphia Using Spatial Regression
Genetic screening for single-cell variability modulators driving therapy resistance
Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility
Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting
ClampFISH detects individual nucleic acid molecules using click chemistry–based amplification
Visualizing adenosine to inosine RNA editing in single mammalian cells
An Alzheimer’s disease-derived biomarker signature identifies Parkinson’s disease patients with dementia
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another?
Conditionals by inversion provide a universal method for the generation of conditional alleles
misc
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Cellular engineering and therapies
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Cellular engineering and therapies
Harnessing mechanisms of gene regulation
Virus evolution and immune evasion
Virus-neutralizing antibodies
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